Platform

Level Nine is a platform that rebuilds catalysts from first principles.

Break it down

We break biological catalytic machinery down to its fundamental building blocks, work out what makes it function, and rebuild it for industry. Machine learning makes that search possible at scale, across a design space far larger than any lab could test.

Redesign it from first principles

We reproduce that fraction as a small synthetic structure, designed for industrial conditions from the start rather than adapted to survive them.

High-throughput testing

Machine learning generates and evaluates candidates against activity, structure and synthetic route, at a scale no laboratory could test by hand.

Tailor-made for industrial needs

Scientific elegance is not the test. The test is whether a catalyst survives real feedstock, real conditions and real economics, which is why process development and scale-up sit inside the platform rather than after it.

NHase: Taking the first industrial biocatalyst and rebuilding it.

Water pouring from a tipped glass
NHaseCS1PlatformCase studyAcrylamide

NHase was biology’s first major industrial win. Rebuilding it proves our platform can replace complex enzymes with simple, robust synthetic structures.

NHase is the ultimate benchmark for our platform. Achieving superior performance in harsher conditions to unlock new possibilities.

We modelled the tiny fraction of the active site that does the work, discarded the protein around it, and rebuilt it as a small synthetic structure.

A major milestone for our computational platform. A catalyst with enzymatic precision with the durability of a traditional catalyst.

Routes

Our development pipeline

One Platform. Endless Possibilities.

Work with us

We run pilot projects with partners, pointing the platform at a target you define. If you have a feedstock you cannot process economically, or a molecule you cannot reach, that is the conversation we want to be in.

Get in touch